American Airlines adds daily Chicago flight to TRI

American Airlines will offer a flight to Chicago from Tri-Cities Airport starting May 21, 2026. The announcement was made by Tri-Cities Airport Thursday morning. The flight to Chicago O’Hare International Airport will operate once daily, with the flight leaving in the morning around 6:30 or 7 a.m. and returning the same evening. The aircraft will make the daily trip with 66 seats, but the airlines could upgrade to a larger plane with more traffic. The flight features first-class and regular class options. Ticket sales will be available online starting Monday morning.